Bikam
Bikam Pharmaceuticals is a drug discovery company focused on developing novel therapies for diseases of the eye with exceptionally high unmet medical need. The initial focus of the company will be on treatments for retinitis pigmentosa, a rare and incurable genetic disease that leads to blindness.
CardioKine is a pharmaceutical company focused on the development of lixivaptan, an oral compound under development for the potential treatment of hyponatremia in patients with congestive heart failure.
EnVivo Pharmaceuticals is a biopharmaceutical company dedicated to discovering and developing
therapeutics for disorders of the central nervous system (CNS).
FoldRx Pharmaceuticals is a mid-stage biotechnology company focused on creating disease modifying drug therapies for diseases of protein misfolding, including amyloidoses and neurodegenerative diseases.
Ikano Therapeutics is a specialty
pharmaceutical company focused on developing nasally delivered pharmaceutical products for well-identified niche markets where rapid onset and nasal delivery should provide medical and commercial advantages, including pain and seizure control.
Ironwood Pharmaceuticals is a mid-stage biotechnology company with programs in late-stage clinical development for gastrointestinal disorders. The company's lead drug candidate, linaclotide, has potential applications in both irritable bowel syndrome and chronic constipation.
LigoCyte Pharmaceuticals is a vaccine discovery and development company focused on norovirus, a pathogen that is a leading cause of viral gastroenteritis (stomach flu). LigoCyte is also developing an influenza vaccine.
Mersana Therapeutics is a drug development company based on Fleximer, a proprietary product platform. Fleximer is a patent-protected polymer used to modify the safety and efficacy of injected drugs. The company’s current focus is on using Fleximer to create and develop commercially-attractive
small molecule cancer drugs based on known drugs or drug classes. Their creation and development can therefore be faster, less expensive, and less risky than new drug discovery while still generating the full patent protection necessary to maximize value creation.
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NeuroTherapeutics Pharma, Inc. (NTP) is a biopharmaceutical company focused on developing therapies for diseases associated with central nervous system hyper-excitability. The company is working with novel mechanisms that will generate first-in-class therapeutics, thereby changing the standard of care for patients
suffering from epilepsy, neuropathic and acute pain, and other disorders of the nervous system.
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NextWave Pharmaceuticals is a specialty pharmaceutical company seeking to create and promote differentiated
products in the pediatric market. NextWave’s products include improved oral liquid formulations of generic
FDA-approved drugs and nutritional supplements. NextWave has partnered with Tris
Pharmaceuticals to develop oral liquid formulations that provide superior taste and extended-release of the active drug.
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NovaMed Pharmaceuticals is a revenue-generating specialty pharmaceutical company focused on commercialization of branded innovative therapies for diseases with high unmet medical need in China, including oncology, urology, and cardiovascular.
Proteostasis Therapeutics
Proteostasis Therapeutics is a drug discovery company focused on developing novel therapies for new therapeutics that control the body's natural protein homeostasis or "Proteostasis Network."
Respivert
Respivert is a drug discovery and development company focused on inhaled therapies for severe respiratory disease.
The company is based in the United Kingdom, and was founded by a team of experienced respiratory drug developers
from GlaxoSmithKline and a leading academic to focus on
products for inhaled delivery.
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Tetraphase Pharmaceuticals discovers and develops new tetracycline-class drugs leveraging a dynamic chemistry engine developed by Dr. Andrew Myers and exclusively licensed from Harvard. The first application of this technology is to develop new antibiotics to treat drug-resistant infections.
Topaz is a later-stage pediatric specialty pharmaceutical company developing a topical prescription product for the treatment of head lice. The company has developed a head lice treatment that is a novel formulation of an approved drug with a long history of safe use as an oral antiparasitic.
Transave is a mid-stage pharmaceutical company whose mission is to improve the treatment of serious lung diseases through the company's next generation, proprietary liposomal delivery technology. The company's lead product is in mid-stage clinical trials for cystic fibrosis and bronchiectasis.
Vicept Therapeutics is an early-stage dermatology specialty pharmaceutical company developing a topical prescription product for the treatment of rosacea, a chronic skin condition characterized by persistent facial erythema (i.e., redness) and acne-like pustules, that affects nearly 14 million Americans aged 20-65.
Wuxi Pharma Tech is a leading provider of R&D pharmaceutical services, specializing in chemistry research, from lead discovery, optimization, bioanalytical and biology services and development to commercial manufacturing.
Medical Devices and Tools
Accuri Cytometers is a life sciences tools company that has developed a novel instrument for the $1B+ flow cytometry market. The company was founded by a creative team with a mission to develop a more affordable flow cytometer.
Acorn Cardiovascular is a later-stage medical device company pursuing an innovative cardiac support device for patients with advanced heart failure. Acorn's CorCap device is intended to prevent and reverse the progression of heart failure by improving the heart's structure and function.
Bioconnect Systems is a medical device company developing products for vascular and general surgeons. Its first product is the OptiFlow AV, a small polymer conduit for connecting an artery to a vein in order to form an arterio-venous (A/V) fistula for renal dialysis access.
TCT Medical, Inc.
TCT Medical is a diagnostic company in China providing high quality diagnostic tests, primarily in the
women's health arena. With an extensive and expanding direct national sales network and strong brand name
in the Ob/Gyn clinical community, TCT is well positioned to become an attractive commercialization platform of
innovative medical devices serving women's health in China.
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US Genomics is a biodefense and diagnostics company currently focused on two main projects. First, the company is developing a biosensor for pathogen detection that, if successful, may be placed in thousands of public locations through Homeland Security’s Biowatch program.
Second, the company has been developing fast identification diagnostics for pathogens in the clinical setting while co-develop a high-throughput testing method for Fragile X and other diseases with a similar genetic basis with Quest Diagnostics.
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ViewRay is an early-stage medical device company focused on developing the Renaissance, an MRI-based image-guided radiation therapy device for cancer patients.